This book explores the intelligent autonomous control problems for spacecraft with multiple constraints, such as pointing/path constraints, linear/angular velocity constraints, performance constraints, etc. It provides an almost self-contained presentation of dynamics modeling, controller design and analysis, as well as simulation studies. The book aims to offer a valuable guide for researchers and aerospace engineers to address the theoretical and technical difficulties in different applications, ranging from spacecraft attitude reorientation and tracking to spacecraft proximity operations, and is mainly intended for technical and engineering staff engaged in spacecraft dyanmics and control areas.