000 01717 a2200241 4500
003 OSt
020 _a9781782624240
040 _cIITK
041 _aeng
082 _a615.3
_bAn87
245 _aAntibiotic drug discovery
_bnew targets and molecular entities
_cedited by Steven M. Firestine and Troy Lister
260 _bThe Royal Society of Chemistry
_c2017
_aLondon
300 _axv, 271p
440 _aDrug discovery series
490 _a / edited by David Thurston
_vno. 58
505 _a
520 _aRecent years have seen a resurgence of antibiotic drug discovery. This book brings together the relevant information to assess the state-of-the-art. It identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new targets, mechanisms and molecular entities. Addressing the need for continued investment in antibiotic drug development, the book provides a point of reference for the rapidly expanding infectious disease research community. In addition to its attention on new targets, the book focusses on the medicinal chemistry and chemistry of the targets. Within this framework, chapters from leading researchers in academia and industry address findings in important areas such as biofilm production, narrow spectrum antibiotics and novel antibacterials from previously uncultured soil bacteria. This book will be a useful resource for postgraduate students and researchers in medicinal chemistry wishing to understand the latest approaches to antibiotic drug discovery
650 _aAntibiotics research
650 _aDrug discovery
700 _aFirestine, Steven M. [ed.]
700 _aLister, Troy [ed.]
942 _cBK
999 _c557945
_d557945