000 01635 a2200229 4500
005 20190114123117.0
008 190114b xxu||||| |||| 00| 0 eng d
020 _a9781118605400
040 _cIIT Kanpur
041 _aeng
082 _a547.2
_bEf41
245 _aEfficiency in natural product total synthesis
_cedited by Pei-Qiang Huang, Zhu-Jun Yao and Richard P. Hsung
260 _bWiley
_c2018
_aNew Jersey
300 _axviii, 493p
520 _aUniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals
650 _aNatural products - synthesis
650 _aOrganic compounds - synthesis.
700 _aHuang, Pei-Qiang [ed.]
700 _aYao, Zhu-Jun [ed.]
700 _aHsung, Richard P. [ed.]
942 _cBK
999 _c559986
_d559986