000			01783 a2200241 4500
003			OSt
005			20210706094946.0
008			210204b xxu||||| |||| 00| 0 eng d
020			_a9783319199207
040			_cIIT Kanpur
041			_aeng
082			_a572 _bB986f2
100			_aBuxbaum, Engelbert
245			_aFundamentals of protein structure and function [2nd ed.] [Perpetual] _cEngelbert Buxbaum
250			_a2nd ed.
260			_bSpringer _c2015 _aHeidelberg
300			_axvi, 521p
520			_aThis book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion of how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological, and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments, and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure, and molecular interactions. The book emphasises the link between protein structure, physiological function, and medical significance.
650			_aProteins -- Structure
650			_aBiochemistry
856			_uhttps://link.springer.com/book/10.1007/978-3-319-19920-7
942			_cEBK
999			_c563539 _d563539